| Identification | Back Directory | [Name]
AZD-7687 | [CAS]
1166827-44-6 | [Synonyms]
AZD7687
AZD-7687
AZD 7687
[trans-4-[4-(6-Carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Cyclohexaneacetic acid, 4-[4-[6-(aminocarbonyl)-3,5-dimethyl-2-pyrazinyl]phenyl]-, trans- | [Molecular Formula]
C21H25N3O3 | [MDL Number]
MFCD23098776 | [MOL File]
1166827-44-6.mol | [Molecular Weight]
367.44 |
| Chemical Properties | Back Directory | [Boiling point ]
527.5±50.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Powder | [pka]
4.72±0.10(Predicted) | [color ]
Off-white to pink |
| Hazard Information | Back Directory | [Uses]
AZD7687 is a novel, potent, selective and reversible inhibitor of diglyceride acyltransferase-1 (DGAT-1). | [in vivo]
Prolonged pharmacological inhibition of DGAT1 with AZD7687 in mice results in the same skin phenotype, including sebaceous gland atrophy and alopecia, as seen in the skin of DGAT1-/- mice. AZD7687-mediated effects on the skin were dose- and time-dependent and reversible[3]. |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|