| Identification | Back Directory | [Name]
2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester | [CAS]
1160293-22-0 | [Synonyms]
methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmet...
methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-Methyl 3-(Methoxy(phenyl)Methylene)-2-oxoindoline-6-carboxylate
(E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Methyl 3-[Methoxy(Phenyl)Methylene]-2-Oxoindoline-6-Carboxylate (Under Development)
2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester
3-(Methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester | [Molecular Formula]
C18H15NO4 | [MDL Number]
MFCD28139165 | [MOL File]
1160293-22-0.mol | [Molecular Weight]
309.32 |
| Chemical Properties | Back Directory | [Melting point ]
>220oC (dec.) | [Boiling point ]
523.8±50.0 °C(Predicted) | [density ]
1.273±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.62±0.20(Predicted) | [color ]
Light Yellow |
| Hazard Information | Back Directory | [Uses]
(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity. |
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