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Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1]. | [Definition]
ChEBI: Spiramine A is a diterpenoid. It derives from a hydride of an atisane. | [References]
[1] Li L, et al. Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica. Eur J Pharmacol. 2002 Aug 2;449(1-2):23-8. DOI:10.1016/s0014-2999(02)01627-8 |
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