| Identification | Back Directory | [Name]
Z-DEVD-AFC | [CAS]
1135416-11-3 | [Synonyms]
Z-DEVD-AFC
Z-ASP-GLU-VAL-ASP-AFC
CASPASE-3, SUBSTRATE IV
CASPASE-3, SUBSTRATE, FLUOROGENIC
Z-ASP-GLU-VAL-ASP-AFC: Z-DEVD-AFC
CASPASE-3 SUBSTRATE IV, FLUOROGENIC
CASPASE-3, SUBSTRATE IV ;Z-ASP-GLU-VAL-ASP-AFC
7-AMINO-4-TRIFLUOROMETHYLCOUMARIN, N-CBZ-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTIC ACID AMIDE | [Molecular Formula]
C36H38F3N5O14 | [MDL Number]
MFCD01074977 | [MOL File]
1135416-11-3.mol | [Molecular Weight]
821.71 |
| Hazard Information | Back Directory | [Uses]
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1]. | [References]
[1] Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25(3):464-472. DOI:10.1016/j.nbd.2006.10.023 |
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