| Identification | Back Directory | [Name]
(5Z)-5-[(3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | [CAS]
1134203-12-5 | [Synonyms]
ATPase-IN-3
4-Thiazolidinone, 5-[(3-nitrophenyl)methylene]-2-thioxo-, (5Z)-
(5Z)-5-[(3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | [Molecular Formula]
C10H6N2O3S2 | [MDL Number]
MFCD00111259 | [MOL File]
1134203-12-5.mol | [Molecular Weight]
266.3 |
| Chemical Properties | Back Directory | [Melting point ]
263-264 °C(Solv: ethanol (64-17-5)) | [density ]
1.60±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
7.03±0.30(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
ATPase-IN-3 (compound 6) is a ATPase inhibitor. ATPase-IN-3 has Gastroprotective effect in ethanol-induced gastric ulcers by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins[1]. | [References]
[1] Ameen RQ, et al. Gastroprotective effect of rhodanine and 2,4-thiazolidinediones scaffolds in rat stomachs by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins. Sci Rep. 2024;14(1):1699. Published 2024 Jan 19. DOI:10.1038/s41598-024-51446-4 |
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| Company Name: |
Merck KGaA
|
| Tel: |
(+86) 21 2033 8288 |
| Website: |
http://www.sigmaaldrich.cn |
| Company Name: |
OTAVA chemicals
|
| Tel: |
416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
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