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ChemicalBook--->CAS DataBase List--->1123491-15-5

1123491-15-5

1123491-15-5 Structure

1123491-15-5 Structure
IdentificationBack Directory
[Name]

5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
[CAS]

1123491-15-5
[Synonyms]

DMPQ (hydrochloride)
[Molecular Formula]

C16H16Cl2N2O2
[MDL Number]

MFCD02262123
[MOL File]

1123491-15-5.mol
[Molecular Weight]

339.216
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

H2O: >10mg/mL
[form ]

powder
[color ]

white to beige
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

DMPQ dihydrochloride is a selective an a potent inhibitor of human platelet-derived growth factor receptor β (PDGFRβ).
[Biological Activity]

DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC50 = 80 nM. It is > 100-fold selective over EGFRerbB2p56protein kinase A and protein kinase C.
[storage]

Store at RT
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