| Identification | Back Directory | [Name]
(R)-TERT-LEUCINOL | [CAS]
112245-09-7 | [Synonyms]
H-D-TLE-OL
D-T-LEUCINOL
H-D-(TBU)GLY-OL
D-Tert-Leucinol
(R)-TERT-LEUCINOL
D-T-BUTYLGLYCINOL
(R)-(-)-TERT-LEUCINOL
D-ALPHA-T-BUTYLGLYCINOL
D-tert-Leucinol,99%e.e.
(R)-(-)-tert-Leucinol 98%
(R)-TERT-LEUCINOL USP/EP/BP
(R)-2-AMINO-3,3-DIMETHYL-1-BUTANOL
(2R)-2-Amino-3,3-dimethylbutan-1-ol
(R)-(-)-tert-Leucinol
(2R)-2-Amino-3,3-dimethylbutan-1-ol 98%
1-Butanol, 2-amino-3,3-dimethyl-, (2R)-
(R)-()-tert-Leucinol,(R)-2-Amino-3,3-dimethyl-1-butanol
D-tert-Leucinol, (2R)-2-Amino-3,3-dimethyl-1-hydroxybutane | [Molecular Formula]
C6H15NO | [MDL Number]
MFCD01076574 | [MOL File]
112245-09-7.mol | [Molecular Weight]
117.19 |
| Chemical Properties | Back Directory | [Melting point ]
30-33 °C(lit.)
| [Boiling point ]
70 °C0.4 mm Hg(lit.)
| [density ]
0.9 g/mL at 25 °C(lit.)
| [Fp ]
194 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Liquid | [pka]
12.88±0.10(Predicted) | [color ]
Colorless to yellow | [optical activity]
[α]20/D 37°, c = 1.5 in ethanol | [InChI]
InChI=1S/C6H15NO/c1-6(2,3)5(7)4-8/h5,8H,4,7H2,1-3H3/t5-/m0/s1 | [InChIKey]
JBULSURVMXPBNA-YFKPBYRVSA-N | [SMILES]
C(O)[C@H](N)C(C)(C)C |
| Hazard Information | Back Directory | [Uses]
(R)-Tert-leucinol (H-D-Tle-ol) is a chiral molecular compound with optical activity and its enantiomeric form is (S)-tert-leucinol. (R)-Tert-leucinol belongs to the class of α-amino alcohols, which have certain biological activities and are potent reversible inhibitors of protein synthesis. (R)-Tert-leucinol can be used as a chiral ligand for asymmetric catalytic reactions. Its derivatives are also used as optical splitting reagents, for peptidyl alcohol synthesis in peptide drugs, and as inhibitors of protein hydrolysis. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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