| Identification | Back Directory | [Name]
-Hydroxypyruvic acid | [CAS]
1113-60-6 | [Synonyms]
3-Hydroxypyruvate
hydroxypyruvic aci
3-hydroxypyruvicaci
3-HYDROXYPYRUVIC ACID
β-hydroxypyruvic acid
β-hydroxy Pyruvic Acid
-Hydroxypyruvic acid
3-HYDROXY-2-OXOPROPIONICACID
3-hydroxy-2-oxopropanoic acid
B-hydroxypyruvic acid free acid
Propanoic acid, 3-hydroxy-2-oxo-
Decanoic acid, ester with 2-ethyl-2-(hydroxymethy)-1,3-propanediol octanoate | [Molecular Formula]
C3H4O4 | [MDL Number]
MFCD00083380 | [MOL File]
1113-60-6.mol | [Molecular Weight]
104.06 |
| Chemical Properties | Back Directory | [Melting point ]
202℃ (ethanol ) | [Boiling point ]
252.9±23.0 °C(Predicted) | [density ]
1.546±0.06 g/cm3(Predicted) | [FEMA ]
3843 | 3-HYDROXY-2-OXOPROPIONIC ACID | [storage temp. ]
2-8°C | [solubility ]
10mg/mL in PBS, pH7.2 | [form ]
Solid | [pka]
2.19±0.54(Predicted) | [color ]
Off-white to light brown | [Odor]
at 1.00 % in propylene glycol. sour radish cabbage | [Odor Type]
sour | [JECFA Number]
635 | [LogP]
-2.04 |
| Hazard Information | Back Directory | [Occurrence]
Reported found in blue cheese, provolone cheese, beer and cocoa | [Uses]
β-Hydroxypyruvic Acid is a metabolite involved in the pathway of carbon in photorespiration. It can also be used to treat fiber. | [Definition]
ChEBI: A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism. | [Biochem/physiol Actions]
Metabolite involved in the pathway of carbon in photorespiration. | [in vivo]
Hydroxypyruvic acid (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats[1]. | Animal Model: | SD rat[1] | | Dosage: | 100 mg/ml; slowly over 10 min | | Administration: | Intravenous injection | | Result: | Led to a significant increase of urinary oxalate and glycolate excretion in both control and vitamin-B6-deficient rats, but these changes are exaggerated in the vitamin-B6-deficient group. |
| [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
|
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