| Identification | Back Directory | [Name]
coformycin | [CAS]
11033-22-0 | [Synonyms]
coformycin
5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-d-ribofuranosyl-imidazo((
(8R)-3,4,7,8-Tetrahydro-3-β-D-ribofuranosylimidazo[4,5-d][1,3]diazepin-8-ol
(8R)-3-β-D-Ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
(r)-3,4,7,8-tetrahydro-3-beta-d-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-o
Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-β-D-ribofuranosyl-, (8R)- | [Molecular Formula]
C11H16N4O5 | [MDL Number]
MFCD00036884 | [MOL File]
11033-22-0.mol | [Molecular Weight]
284.27 |
| Hazard Information | Back Directory | [Description]
Coformycin is isolated from Nocardia
interforma along with formycin. Coformycin
shows a synergistic effect with
formycin on Yoshida rat sarcoma cells because
of its strong inhibition of adenosine deaminase,
which inactivates formycin. Coformycin, having
a characteristic seven-membered ring base
moiety, is thought to be a typical example of a
“transition-state analog” in the adenosine deaminase
reaction. 2_x0002_-Deoxycoformycin (19b) has
also been isolated also . | [Definition]
ChEBI: An N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N3-glycosidic bond. compound The
parent of the class of coformycins. |
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