Identification | Back Directory | [Name]
senfolomycin B | [CAS]
11031-56-4 | [Synonyms]
senfolomycin B 5-[6-(acetyloxymethyl)-3-hydroxy-4-[5-hydroxy-5-(1-hydroxyethyl)-4-methoxy-6-methyloxan-2-yl]oxy-5-[(Z)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-(1-hydroxyethyl)-3-O-methyl-α-L-xylo-hexopyranosyl]-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)- | [Molecular Formula]
C29H38N2O16S | [MOL File]
11031-56-4.mol | [Molecular Weight]
702.68 |
Hazard Information | Back Directory | [Uses]
Senfolomycin B has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin, Macrolide antibiotics. Senfolomycin A also has weaker effect of anti-Gram-negative bacteria[1]. | [References]
[1] A D Argoudelis, et al. Structural relationships between senfolomycins and paulomycins. J Antibiot (Tokyo). 1988 Sep;41(9):1212-22. |
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