| Identification | Back Directory | [Name]
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) | [CAS]
110025-28-0 | [Synonyms]
4OHNDtam
E/Z Endoxifen
Endoxifen (Z/E=3:2)
(E /Z) Endoxifen HCl
4-hydroxy-N-desmethyltamoxifen
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol
4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
see H938500 | [Molecular Formula]
C25H27NO2 | [MDL Number]
MFCD09840374 | [MOL File]
110025-28-0.mol | [Molecular Weight]
373.493 |
| Chemical Properties | Back Directory | [Appearance]
Brown Foam | [Melting point ]
63-72°C | [Boiling point ]
519.3±50.0 °C(Predicted) | [density ]
1.099±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform, Dichloromethane, DMSO, Methanol | [form ]
Solid | [pka]
9.38±0.15(Predicted) | [color ]
Light Brown to Light Purple |
| Hazard Information | Back Directory | [Chemical Properties]
Brown Foam | [Uses]
A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line. | [Uses]
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca | [storage]
Store at +4°C |
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