| Identification | Back Directory | [Name]
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide | [CAS]
1099592-35-4 | [Synonyms]
NASH
Naphthyl salicylic acyl hydrazone
(E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide
DNA/RNA Synthesis,HCT116,MDA-231,Panc1,Inhibitor,NSAH,inhibit,S-phase
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
Benzoic acid, 2-hydroxy-, (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide | [Molecular Formula]
C18H14N2O3 | [MDL Number]
MFCD00196698 | [MOL File]
1099592-35-4.mol | [Molecular Weight]
306.32 |
| Hazard Information | Back Directory | [Biological Activity]
NSAH is a cell penetrantpotent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cellswhile demonstrated very moderate toxicity against normal blood progenitor cells. |
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| Company Name: |
InvivoChem
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13549236410 |
| Website: |
https://www.invivochem.cn/ |
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