| Identification | Back Directory | [Name]
TAUTOMYCIN | [CAS]
109946-35-2 | [Synonyms]
TAUTOMYCIN
tautomycin from streptomyces spiroverticillatus
TAUTOMYCIN FROM STREPTOMYCES SPIROVERTI- CILLATUS, 50 UG
Tautomycin, Streptomyces spiroverticillatus - CAS 109946-35-2 - Calbiochem
3-Furanpropanoic acid, 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-, (1R,2S,3R,6S,7S,10R)-10-[(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl]-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl ester, (βR)- | [Molecular Formula]
C41H66O13 | [MDL Number]
MFCD00236438 | [MOL File]
109946-35-2.mol | [Molecular Weight]
766.95 |
| Chemical Properties | Back Directory | [Boiling point ]
854.3±65.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [form ]
Lyophilized thin film | [pka]
12.33±0.20(Predicted) | [BRN ]
3583132 |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
28 | [Safety Statements ]
22-28-36/37-45 | [RIDADR ]
UN 3462 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
WX1000000
| [F ]
3-8-10-21 | [Toxicity]
mouse,LD50,intraperitoneal,5mg/kg (5mg/kg),Journal of Antibiotics. Vol. 40, Pg. 907, 1987. |
| Hazard Information | Back Directory | [Uses]
Tautomycin is a potent and specific PP1 and PP2 inhibitor. | [Biological Activity]
Cell permeable: no''Primary Target
PP1''Product does not compete with ATP.''Reversible: no''Target IC50: 1 nM10 nM6 nMagainst protein phosphatase 1protein phosphatase 2Aand smooth muscle endogenous phosphataserespectively | [storage]
Store at -20°C |
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