| Identification | Back Directory | [Name]
(4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine HCL | [CAS]
1092689-33-2 | [Synonyms]
Tetrazine-Amine
Tetrazine – Amine, HCl salt
Tetrazine - Amine - TFA-salt
3-(4-benzylamino)-1,2,4,5-tetrazine
3-(p-benzylamino)-1,2,4,5-tetrazine
3-[4-(aminomethyl)phenyl]-1,2,4,5-tetrazine
4-(1,2,4,5-tetrazin-3-yl)benzenemethanamine
1-[4-(1,2,4,5-tetrazin-3-yl)phenyl]methanamine
Benzenemethanamine, 4-(1,2,4,5-tetrazin-3-yl)-
(4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine HCL
4-(1,2,4,5-tetrazin-3-yl)benzenemethanamine hydrochloride | [Molecular Formula]
C9H9N5 | [MDL Number]
MFCD20275288 | [MOL File]
1092689-33-2.mol | [Molecular Weight]
187.2 |
| Hazard Information | Back Directory | [Uses]
Tetrazine-Amine is a tetrazine linker that can be used to covalently label live cells through a cycloaddition[1][2]. Tetrazine-Amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. | [References]
[1] Devaraj NK, et, al. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009;48(38):7013-6. DOI:10.1002/anie.200903233
[2] Devaraj NK, et, al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19(12):2297-9. DOI:10.1021/bc8004446 |
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