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ChemicalBook--->CAS DataBase List--->1092658-06-4

1092658-06-4

1092658-06-4 Structure

1092658-06-4 Structure
IdentificationBack Directory
[Name]

Ensituximab
[CAS]

1092658-06-4
[Synonyms]

Ensituximab
Research Grade Ensituximab(DHF78601)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer[1][2].
[References]

[1] Richard D Kim, et al. Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer. Clin Cancer Res. 2020 Jul 15;26(14):3557-3564. DOI:10.1158/1078-0432.CCR-20-0426
[2] Julian A Marin-Acevedo, et al. Cancer immunotherapy beyond immune checkpoint inhibitors. J Hematol Oncol. 2018 Jan 12;11(1):8. DOI:10.1186/s13045-017-0552-6
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