| Identification | Back Directory | [Name]
5-(piperazin-1-yl)pyridin-2-aMine | [CAS]
1082876-26-3 | [Synonyms]
Palbociclib-005
Palbociclib Impurity 44
5-(1-Piperazinyl)-2-pyridinamine
2-Amino-5-(1-piperazinyl)pyridine
5-(piperazin-1-yl)pyridin-2-aMine
5-Piperazin-1-yl-pyridin-2-ylamine
2-Pyridinamine, 5-(1-piperazinyl)-
Palbociclib impurity 6/5-(piperazin-1-yl)pyridin-2-amine | [Molecular Formula]
C9H14N4 | [MOL File]
1082876-26-3.mol | [Molecular Weight]
178.23 |
| Chemical Properties | Back Directory | [Boiling point ]
401.7±40.0 °C(Predicted) | [density ]
1.163±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
8.67±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
5-?(1-?Piperazinyl)?-?2-?pyridinamine is a reagent used in the synthesis of anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. |
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