| Identification | Back Directory | [Name]
Apixaban Dehydro Impurity | [CAS]
1074549-89-5 | [Synonyms]
Dehydro Apixaban
4,5-Dehydro Apixaban
Apixaban Impurity TQ
Apixaban 4,5-Dehydro Imp
Apixaban Dehydro Impurity
Apixaban 4,5-Dehydro Impurity
Apixaban 4,5-Dehydro Carboxamide
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 6,7-dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-
Apixaban impurity 11/4,5-Dehydro Apixaban/Apixaban dehydro Impurity/1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C25H23N5O4 | [MOL File]
1074549-89-5.mol | [Molecular Weight]
457.48 |
| Chemical Properties | Back Directory | [Melting point ]
>252°C (dec.) | [Boiling point ]
770.0±60.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
14.67±0.20(Predicted) | [color ]
White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
4,5-Dehydro Apixaban is an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation |
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