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ChemicalBook--->CAS DataBase List--->106392-48-7

106392-48-7

    106392-48-7 Structure

    106392-48-7 Structure
    IdentificationBack Directory
    [Name]

    2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-
    [CAS]

    106392-48-7
    [Synonyms]

    ST 271
    ST271, >98%
    ST271;ST 271;ST-271
    2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-
    [Molecular Formula]

    C16H20N2O2
    [MDL Number]

    MFCD31544351
    [MOL File]

    106392-48-7.mol
    [Molecular Weight]

    272.34
    Chemical PropertiesBack Directory
    [Boiling point ]

    468.4±45.0 °C(Predicted)
    [density ]

    1.137±0.06 g/cm3(Predicted)
    [storage temp. ]

    Sealed in dry,2-8°C
    [solubility ]

    DMSO : ≥ 110 mg/mL (403.91 mM)
    [form ]

    Solid
    [pka]

    10.05±0.40(Predicted)
    [color ]

    Light yellow to yellow
    Safety DataBack Directory
    [Symbol(GHS) ]


    GHS07
    [Signal word ]

    Warning
    [Hazard statements ]

    H302-H315-H319-H335
    [Precautionary statements ]

    P261-P305+P351+P338
    Hazard InformationBack Directory
    [Biological Activity]

    ST271 is a tyrosine phosphorylation inhibitor that inhibits phospholipase D activity.
    [in vitro]

    ST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30% ) but significant inhibition of the response to thrombin and U46619.

    [target]

    TargetValue
    PLD
    ()
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