| Identification | Back Directory | [Name]
Tubulin inhibitor 6 | [CAS]
105925-39-1 | [Synonyms]
iHAP1
Tubulin inhibitor 6
Methanone, (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)- | [Molecular Formula]
C20H14ClNO2S | [MOL File]
105925-39-1.mol | [Molecular Weight]
367.85 |
| Chemical Properties | Back Directory | [Melting point ]
155-157 °C | [Boiling point ]
549.1±50.0 °C(Predicted) | [density ]
1.364±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 62.5 mg/mL (169.91 mM) | [form ]
A crystalline solid | [pka]
-5.56±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
Tubulin inhibitor 6 is an activator of protein phosphatase 2A (PP2A) enzymes that activates PP2A-B56ε and efficiently kills malignant cells. | [in vitro]
Tubulin inhibitor 6 displays submicromolar antiproliferative activity. | [target]
| Target | Value | PP2A
() | [storage]
Store at -20°C |
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| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
|
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Tags:105925-39-1
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