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ChemicalBook--->CAS DataBase List--->105613-90-9

105613-90-9

105613-90-9 Structure

105613-90-9 Structure
IdentificationBack Directory
[Name]

(1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-
[CAS]

105613-90-9
[Synonyms]

Fluticasone EP Imp E
Fluticasone Furoate Impurity J
Androst-4-ene-17-carbothioic acid
1,2-Dihydro Fluticasone Propionate
Fluticasone Propinate EP impurity E
Fluticasone Propionate EP Impurity E
6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-
Fluticasone Impurity 5(Fluticasone EP Impurity E)
(1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-
(1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-
6α,9-difluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]- 11β-hydroxy-16α-methyl-3-oxoandrost-4-en-17α-yl propanoate
Androst-4-ene-17-carbothioic acid,6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,S-(fluoromethyl) ester,(6α,11β,16α,17α)
Androst-4-ene-17-carbothioic acid, 6,9-difluoro-11-hydroxy- 16-Methyl-3-oxo-17-(1- oxopropoxy)-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)-
Androst-4-ene-17-carbothioicacid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,S-(fluoromethyl) ester, (6a,11b,16a,17a)- (9CI)
(6α,8ξ,11β,14ξ,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl] carbonyl}-11-hydroxy-16-methyl-3-oxoandrost-4-en-17-yl propionate
Fluticasone Propionate EP Impurity E/1,2-Dihydro Fluticasone Propionate/6α,9-Difluoro-17-[[(fluoromethyl)sulphanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrost-4-en-17α-yl propanoate
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylpropionate
(6α,8ξ,11β,14ξ,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl] carbonyl}-11-hydroxy-16-methyl-3-oxoandrost-4-en-17-yl propionate
[Molecular Formula]

C25H33F3O5S
[MDL Number]

MFCD21363603
[MOL File]

105613-90-9.mol
[Molecular Weight]

502.59
Chemical PropertiesBack Directory
[Melting point ]

196-199°C (dec.)
[Boiling point ]

567.9±50.0 °C(Predicted)
[density ]

1.30±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.62±0.70(Predicted)
[color ]

White to Light Brown
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H334-H312-H302-H332-H360
[Precautionary statements ]

P261-P271-P304+P340-P312-P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

1,2-Dihydro Fluticasone Propionate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory.
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