| Identification | Back Directory | [Name]
2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE | [CAS]
105350-26-3 | [Synonyms]
SR2640HCl
SR 2640 HYDROCHLORIDE
2-[[3-[(Quinolin-2-yl)methoxy]phenyl]amino]benzoic acid
2-[3-(2-Quinolylmethoxy)phenylamino]benzoic acid hydrochloride
2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE
2-((3-(Quinolin-2-ylMethoxy)phenyl)aMino)benzoic acid hydrochloride | [Molecular Formula]
C23H18N2O3 | [MDL Number]
MFCD04971976 | [MOL File]
105350-26-3.mol | [Molecular Weight]
370.4 |
| Chemical Properties | Back Directory | [Melting point ]
>136°C (dec.) | [Boiling point ]
580.3±45.0 °C(Predicted) | [density ]
1.322±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 50 mg/mL, soluble | [form ]
solid | [pka]
3.67±0.36(Predicted) | [color ]
yellow, powder with a tan cast | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
SR 2640 Hydrochloride is a useful intermediate. It is a potent, selective LTD4 /LTE4 receptor antagonist. | [Definition]
ChEBI:2-[3-(2-quinolinylmethoxy)anilino]benzoic acid is a member of quinolines. | [Biological Activity]
Potent and selective competitive leukotriene D 4 and E 4 receptor antagonist. Inhibits LTD 4 - but not histamine-induced guinea pig ileum and trachea contraction (pA 2 = 8.7). Also inhibits LTD 4 -attenuation of human PMN chemotaxis. Orally active in vivo . |
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