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ChemicalBook--->CAS DataBase List--->105228-46-4

105228-46-4

105228-46-4 Structure

105228-46-4 Structure
IdentificationBack Directory
[Name]

Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
[CAS]

105228-46-4
[Synonyms]

6-oxo-2
Benzyl (2S
3-diphenyl-
4-Morpholinecarboxylicacid
(2S,3R)-N-CBZ-6-OXO-2,3- DIPHENYLMORPHOLINE
(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine
(2S,3R)-benzyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate
(5S,6R)-(+)-4-Benzyloxycarbonyl-5,6-diphenyl-2-Morpholinone
(2S,3R)-(+)-N-Benzyloxycarbonyl-6-oxo-2,3-diphenylMorpholine
BENZYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
Benzyl (2S,3R)-6-Oxo-2,3-diphenyl-4-morpholinecarbox ylate,99%e.e.
(2S,3R)-6-oxo-2,3-diphenyl-4-morpholinecarboxylic acid (phenylmethyl) ester
4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2S,3R)-
(5R,6S)-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one
(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine
[Molecular Formula]

C24H21NO4
[MDL Number]

MFCD00074956
[MOL File]

105228-46-4.mol
[Molecular Weight]

387.43
Chemical PropertiesBack Directory
[Melting point ]

205-207 °C(lit.)
[alpha ]

66 º (c=5.5 in methylene chloride)
[Boiling point ]

583.5±50.0 °C(Predicted)
[density ]

1.242±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

-3.33±0.60(Predicted)
[optical activity]

[α]25/D +66°, c = 5.5 in methylene chloride
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-37/39
[WGK Germany ]

3
[HS Code ]

29349990
Hazard InformationBack Directory
[Uses]

(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine can be used as a starting material for the synthesis of:
  • α-Amino-β-silyloxy-ester, a key intermediate for the preparation of antimalarial drug quinine and its analogs.
  • R, R-Formylglycine dimethylacetal, a key intermediate for the preparation of tuberculostatic compound capreomycin IB.
  • 2R,5R,6S-2-(Methoxycarbonylmethyl)-5,6-diphenylmorpholine hydrochloride, a key intermediate for the preparation of an antibiotic (+)-negamycin.

Spectrum DetailBack Directory
[Spectrum Detail]

Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate(105228-46-4)1HNMR
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate(105228-46-4)Raman
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate(105228-46-4)IR
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