| Identification | Back Directory | [Name]
Ceftriaxone sodium | [CAS]
104376-79-6 | [Synonyms]
Rosihlitazone
CEFTRIAXONE NA
RO-13-9904/001
Hemiheptahydrate
ROCEFIN ROCEPHINE
CEFTRIASONE SODIUM
CEFTRIAXONE SODIUM INJ
CEFTRIAXONE SODIUM SALT
CEFTRIAXONE SODIUM HYDRATE
Ceftriaxone sodium sterile
Ceftriaxone Sodium (350 mg)
Ceftriaxone SodiuM Trihydrate
CeftriaxoneSodiumSterileUsp26
Ceftriaxone Sodium(Nonsterile)
Disodium salt hemiheptahydrate
Ceftriaxone Disodium Salt
CEFTRIAXONE SODIUM FOR INJECTION
Ceftriaxone (sodium salt hydrate)
Ro-13-9904/001, Rocefin Rocephine
Ceftriaxone sodiuM sesquaterhydrate
CEFTRIAXONE, DISODIUM SALT, HEMIHEPTAHYDRATE
Ceftriaxone Sodium (350 mg)G1D265925ug/mg(an)
Ceftriaxone hemi(heptahydrate) disodium salt
Ceftriaxone disodium salt hemiheptahydrate, >=98%
(6r,7r)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
(6R,7R)-7-[(Z)-2-2(2-Amino-4-thiazolyl)-2-(methoxyimino)azetamido]-3-{[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-aza-bicyclo-[4.2.0]oct-2-en-2-carbonsure-dinatriumsalz
7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaciddisodiumsalt
[6R-[6α,7β(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Hydrate
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:4:7), (6R,7R)- | [EINECS(EC#)]
277-930-0 | [Molecular Formula]
C18H16N8Na2O7S3.31/2H2O | [MDL Number]
MFCD01750405 | [MOL File]
104376-79-6.mol | [Molecular Weight]
598.54 |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
236 °C | [alpha ]
D25 -165° (c = 1 in water) (calc for water-free substance) | [refractive index ]
-160 ° (C=1, H2O) | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble50mg/mL | [form ]
powder or crystals | [pka]
~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH) | [color ]
White to Off-White | [Water Solubility ]
Freely soluble in water | [InChIKey]
FDRNWTJTHBSPMW-BBJOQENWSA-L |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
A potentially useful antibacterial agent for proteomics research. | [Uses]
An antibacterial, a third-generation cephalosporin. | [Uses]
antipsychotic | [Biological Activity]
β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter. | [Description]
Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.1,2,3 It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.4 | [Definition]
ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin. | [Brand name]
Rocephin (Roche). | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
36/37/38-42/43 | [Safety Statements ]
26-36-45-37-24-22 | [WGK Germany ]
1
| [RTECS ]
XI0368800 | [HS Code ]
29349990 | [Toxicity]
LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman) |
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