Identification | Back Directory | [Name]
EPA | [CAS]
10417-94-4 | [Synonyms]
EPA 92-PGM acid 5, EPA 45G Ropufa 70 ICOSAPENT 5,8,11,14, EPA / DHA 40% C20:5 OMEGA-3 TIMNODONIC ACID EPA 18 / DHA 12 Eicosapentaenoic Incromega E 7010SR Icosapentaenoic Acid EICOSAPENTAENOIC CID EICOSAPENTAENOIC ACID EPA 5C,8C,11C,14C,17C EPA, Timnodonic acid eiosapentaenoic acid,EPA ALL CIS 5-8-11-14-17 EPA EPA 18 / DHA 12 DEODORIZED EPA (Eicosapentaenoic Acid) Eicosapentaenoic acid (EPA) EICOSAPENTAENOIC ACID(EPA)(SG) Eicosapentaenoic acid (EPA) -d5 SEA OIL POWDER 30 EPA 18 / DHA 12 C20:5 (ALL CIS-5,8,11,14,17) ACID 5,8,11,14,17-EICOSAPENTAENOIC ACID Eicosapentaenoic acid-(5,8,11,14,17) CIS-5,8,11,14,17-EICOSAPENTAENOIC AC Eicosapentaenoic Acid (peroxide free) CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID 5,8,11,14,17-eicosapentaenoic acid: EPA cis-5,8,11,14,17-Dicosapentaenoic
acid EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid cis-5,8,11,14,17-Eicosapentaenoic acid ,95% cis-5,8,11,14,17-Eicosapentaenoic acid ,70% 5,8,11,14,17-Eicosapentaenoic acid (all-cis) CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID, 90+% EPA
all cis-5,8,11,14,17-Icosapentaenoic Acid Single-Use Eicosapentaenoic Acid (peroxide free) (2E,4E,6E,8E,10E)-icosa-2,4,6,8,10-pentaenoic acid Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*F REE ACID AP 5,8,11,14,17-EICOSAPENTAENOIC ACID, STAN DARD FOR GC (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Icosapentaenoic acid (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid 5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)- cis-5,8,11,14,17-Eicosapentaenoic acid,EPA, Timnodonic acid | [Molecular Formula]
C20H30O2 | [MDL Number]
MFCD00065716 | [MOL File]
10417-94-4.mol | [Molecular Weight]
302.45 |
Chemical Properties | Back Directory | [Appearance]
Colorless Oil | [Melting point ]
−54-−53 °C(lit.)
| [Boiling point ]
439℃ | [density ]
0.943 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.4977(lit.)
| [Fp ]
93 °C | [storage temp. ]
−20°C
| [solubility ]
Soluble in methanol | [form ]
liquid
| [pka]
4.75±0.10(Predicted) | [color ]
Colorless to pale yellow | [biological source]
fish oil | [Sensitive ]
Air & Light Sensitive | [Merck ]
14,3531 | [BRN ]
1714433 | [Stability:]
Stable for 1 year as supplied (unopened). After opening, EPA must be stored under inert gas at -80°C. Solutions in DMSO or ethanol should also be stored under inert gas and may be kept at -80°C for up to 2 months. | [InChIKey]
RRGOKSYVAZDNKR-ARJAWSKDSA-N | [LogP]
6.232 (est) |
Hazard Information | Back Directory | [Chemical Properties]
Colorless Oil | [Uses]
Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the “methyl end” of the molecule. Antilipemic. | [Definition]
ChEBI: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. | [Description]
Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid.1 Eicosapentaenoic acid has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.2,3
Eicosapentaenoic acid MaxSpec? standard is a quantitative grade standard of eicosapentaenoic acid (Item No. 90110) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This eicosapentaenoic acid MaxSpec? standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. | [Description]
EPA is an ω-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid.1 EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.2,3 | [Brand name]
Decabid (Lilly). | [General Description]
Eicosapentaenoic acid (cis-5,8,11,14,17), also known as EPA, is a long-chain omega-3 fatty acid. Studies suggests that EPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders. This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in mass spectrometry-based EPA testing applications such as assessment of cardiovascular?disease risk and fatty acid deficiency, and detection and quantification of EPA in nutraceuticals and dietary supplements. | [Biochem/physiol Actions]
5-Lipoxygenase inhibitor; reduces thromboxane A2 production. | [References]
1) Lee et al. (1985), Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function; N. Engl. J. Med., 312 1217
2) Nicholson et al. (2013), The role of marine n-3 fatty acids in improving cardiovascular health: a review; Food Funct., 4 357 |
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