| Identification | Back Directory | [Name]
11(α)-methoxysaikosaponin F | [CAS]
104109-37-7 | [Synonyms]
Reaxys ID: 6045609
11(α)-methoxysaikosaponin F
11alpha-Methoxysaikosaponin F
β-D-Glucopyranoside, (3β,11α,16β)-16,28-dihydroxy-11-methoxyolean-12-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]- | [Molecular Formula]
C49H82O18 | [MDL Number]
MFCD30725472 | [MOL File]
104109-37-7.mol | [Molecular Weight]
959.16 |
| Chemical Properties | Back Directory | [Boiling point ]
1007.2±65.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.76±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity[1]. | [References]
[1] Liu X, et al. Bupleurum marginatum Wall.ex DC in Liver Fibrosis: Pharmacological Evaluation, Differential Proteomics, and Network Pharmacology. Front Pharmacol. 2018 May 17;9:524. DOI:10.3389/fphar.2018.00524 |
|
| Company Name: |
Rhawn Reagent
|
| Tel: |
400-400-1332688 18019345275 |
| Website: |
http://www.rhawn.cn |
|