| Identification | Back Directory | [Name]
5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE | [CAS]
102649-78-5 | [Synonyms]
SC-9
N-(6-PHENYLHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE
5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE
5-Chloro-N-(6-phenylhexyl)naphthalene-1-sulfonaMide
N-(6-PHENYLHEXYL)-5-CHLORO-1-*NAPHTHALEN ESULFONAMID | [Molecular Formula]
C22H24ClNO2S | [MDL Number]
MFCD00065544 | [MOL File]
102649-78-5.mol | [Molecular Weight]
401.95 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
75-76°C | [Boiling point ]
577.5±52.0 °C(Predicted) | [density ]
1.220±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly) | [form ]
Off-white crystalline solid. | [pka]
11.25±0.50(Predicted) | [color ]
Off-White to Pale Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Activates protein kinase C in a Ca2+-dependent manner, via a mechanism similar to that of phosphatidylserine. | [Biological Activity]
A potent activator of protein kinase C. | [Definition]
ChEBI: 5-chloro-N-(6-phenylhexyl)-1-naphthalenesulfonamide is a member of naphthalenes and a sulfonic acid derivative. | [References]
[1] Ito M, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. Biochemistry. 1986 Jul 29;25(15):4179-84. DOI:10.1021/bi00363a002
[2] Nishino H, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. Biochim Biophys Acta. 1986 Nov 28;889(2):236-9. DOI:10.1016/0167-4889(86)90109-6 |
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