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ChemicalBook--->CAS DataBase List--->1021934-03-1

1021934-03-1

1021934-03-1 Structure

1021934-03-1 Structure
IdentificationBack Directory
[Name]

(S)-O-Desmethyl Venlafaxine N-Oxide
[CAS]

1021934-03-1
[Synonyms]

(S)-O-Desmethyl Venlafaxine N-Oxide
[Molecular Formula]

C16H25NO3
[MOL File]

1021934-03-1.mol
[Molecular Weight]

279.37
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[pka]

9.84±0.26(Predicted)
Hazard InformationBack Directory
[Uses]

(S)-O-Desmethyl Venlafaxine N-Oxide is a N-oxyde of (S)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
[storage]

Store at -20°C
[References]

[1] Lechoslaw A. Turski, et al. N-oxydes de venlafaxine et de o-desméthylvenlafaxine comme promédicaments. WO2009000797A1.
[2] Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Ch DOI:10.1016/j.chroma.2015.09.088
[3] F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80. DOI:10.1016/S0893-133X(01)00298-6
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