| Identification | Back Directory | [Name]
ATRACTYLOSIDE POTASSIUM SALT | [CAS]
102130-43-8 | [Synonyms]
ATR, 2K
Atractyloside dipotassium
ATRACTYLOSIDE POTASSIUM SALT
ATRACTYLOSIDE, DIPOTASSIUM SALT
Atractyloside dipotassium salt, >=98%
ATRACTYLOSIDE POTASSIUM SALT USP/EP/BP
ATRACTYLOSIDE, DIPOTASSIUM SALT, ATRACTYLIS GUMMIFERA
19-Norkaur-16-en-18-oic acid deriv. 1H-2,10a-Ethanophenanthrene
(2β,15α)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-19-Norkaur-16-en-18-oic Acid Dipotassium Salt
19-Norkaur-16-en-18-oicacid, 15-hydroxy-2-[[2-O-(3-Methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-,dipotassiuM salt, (2b,15a)- (9CI)
(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt
19-Norkaur-16-en-18-oic acid, 15-hydroxy-2-2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-.beta.-D-glucopyranosyloxy-, dipotassium salt, (2.beta.,15.alpha.)- | [Molecular Formula]
C30H44K2O16S2 | [MDL Number]
MFCD00078810 | [MOL File]
102130-43-8.mol | [Molecular Weight]
802.99 |
| Chemical Properties | Back Directory | [Melting point ]
234-238°C | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
H2O: 20 mg/mL
| [form ]
Solid | [color ]
Pale Brown to Pale Beige | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Atractyloside is a natural heteroglucoside produced in some plants, including A. gummifera.1 Atractyloside prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and triphosphates across the inner mitochondrial membrane.1,2 | [Uses]
Atractyloside Dipotassium Salt is an inhibitor of ANT and apoptosis inducer. | [References]
[1]. yamaguchi n, kagari t, kasai m. inhibition of the ryanodine receptor calcium channel in the sarcoplasmic reticulum of skeletal muscle by an adp/atp translocase inhibitor, atractyloside. biochem biophys res commun, 1999, 258(2): 247-251.
[2]. pick-kober kh, schneider f. proliferation, macromolecular synthesis and energy metabolism of in vitro grown ehrlich ascites tumor cells after inhibition of atp-adp translocation by atractyloside. eur j cell biol, 1984, 34(2): 323-329.
[3]. malekova l, kominkova v, ferko m, et al. bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. biochim biophys acta, 2007, 1767(1): 31-44. |
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