| Identification | Back Directory | [Name]
(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol | [CAS]
102036-29-3 | [Synonyms]
Q-100961
FT-0689654
Protosappanin B
(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
(7S,12aS)-7,8-Dihydro-7-(hydroxymethyl)-6H-dibenz[b,d]oxocin-3,7,10,11-tetrol
6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol,7,8-dihydro-7-(hydroxymethyl)-, (7S,12aS)- | [Molecular Formula]
C16H16O6 | [MDL Number]
MFCD29048516 | [MOL File]
102036-29-3.mol | [Molecular Weight]
304.29 |
| Chemical Properties | Back Directory | [Boiling point ]
655.5±55.0 °C(Predicted) | [density ]
1.507 | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [pka]
9.20±0.40(Predicted) | [color ]
Light yellow to orange |
| Hazard Information | Back Directory | [Description]
Research results in recent years have shown that sumac extract has a significant inhibitory effect on a variety of tumor cells. Protosappanin B is one of the main components in hematoxylin. It has inhibitory effect on the proliferation of both BTT and T24 cells, and as Protosappanin B acts on each cell for a longer period of time, its killing effect is gradually enhanced, showing a time-dependence. | [Chemical Properties]
Soluble in methanol, DMSO, insoluble in petroleum ether and other solvents. | [Biological Activity]
Protosappanin B is a polyphenol extracted from hematoxylin and has anti-tumor effects. In human bladder cancer cells, it can arrest the G1 phase of the cell cycle and induce apoptosis. | [target]
| [storage]
4°C, protect from light |
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