Identification | Back Directory | [Name]
sodiuM 4-pentynoate | [CAS]
101917-30-0 | [Synonyms]
sodiuM 4-pentynoate sodium pent-4-ynoate 4-Pentynoic acid,sodium salt Sodium 3-butyne-1-carboxylate | [Molecular Formula]
C5H5O2.Na | [MDL Number]
MFCD22417092 | [MOL File]
101917-30-0.mol | [Molecular Weight]
120.082 |
Hazard Information | Back Directory | [Uses]
Sodium 4-pentynoate is a alkynylacetate analogue, can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types[1]. Sodium 4-pentynoate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Yang YY, et al. Bioorthogonal chemical reporters for monitoring protein acetylation. J Am Chem Soc. 2010 Mar 24;132(11):3640-1. DOI:10.1021/ja908871t |
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