| Identification | Back Directory | [Name]
1,1-bis(4-METHOXYPHENYL)-2-PROPYN-1-OL | [CAS]
101597-25-5 | [Synonyms]
1,1-Di(4-methoxyphenyl)prop-2-yn-1-ol
1,1-Dis(4-methoxphenyl)-2-propyn-1-ol
1,1-Bis(4-methoxyphenyl)prop-2-yn-1-ol
1,1-bis(4-METHOXYPHENYL)-2-PROPYN-1-OL
BenzeneMethanol, a-ethynyl-4-Methoxy-a-(4-Methoxyphenyl)-
Benzenemethanol, α-ethynyl-4-methoxy-α-(4-methoxyphenyl)- | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C17H16O3 | [MDL Number]
MFCD00420323 | [MOL File]
101597-25-5.mol | [Molecular Weight]
268.307 |
| Chemical Properties | Back Directory | [Melting point ]
91.9-92.2℃ | [Boiling point ]
412.0±45.0 °C(Predicted) | [density ]
1.156 | [storage temp. ]
Sealed in dry,2-8°C | [form ]
powder to crystal | [pka]
11.72±0.29(Predicted) | [color ]
White to Almost white |
| Hazard Information | Back Directory | [Uses]
1,1-bis(4-Methoxyphenyl)-2-propyn-1-ol (cas# 101597-25-5) is used in the synthetic preparation of photochromic pyranobenzopyran derivatives. | [Preparation]
The preparation of 1,1-bis(4-methoxyphenyl)-2-propyn-1-ol is as follows:18W % sodium acetylide in xylene/mineral oil 121.1mL (0.45mol, 1eq) was dissolved in anhydrous THF (1L) saturated with acetylene gas. After that 4,4-dimethoxybenzophenone 100g (0.41mol, 1eq) was put inside the reaction mixture under nitrogen and stirred for 24h at room temperature. The product was extracted by solvent extraction using ethyl acetate and water, organic layer was dried with MgSO4 and solid product on vacuum drier. After complete drying, the product again dissolve in ethyl acetate and poured into 1L hexane slowly under stirring which afford 8 as white color solid, yield (99g, 90%).
|
|
|