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ChemicalBook--->CAS DataBase List--->101526-83-4

101526-83-4

101526-83-4 Structure

101526-83-4 Structure
IdentificationBack Directory
[Name]

N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
[CAS]

101526-83-4
[Synonyms]

RU-752
Sematilide
N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
N-(2-Diethylaminoethyl)-4-(methylsulfonylamino)benzamide
N-(2-(DiethylaMino)ethyl)-4-(MethylsulfonaMido)benzaMide
N-[2-(DIETHYLAMINO)ETHYL]-4-(METHANESULFONAMIDO)BENZAMIDE
Benzamide,N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]-
[Molecular Formula]

C14H23N3O3S
[MDL Number]

MFCD00867100
[MOL File]

101526-83-4.mol
[Molecular Weight]

313.42
Chemical PropertiesBack Directory
[density ]

1.205±0.06 g/cm3(Predicted)
[pka]

7.43±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Cardiac depressant (anti-arrhythmic).
[in vivo]

Sematilide (0.3-1.0 mg/kg, intravenously i.v.) is effective in a canine model of arrhythmia[2].

Animal Model:Mongrel dogs of either sex (10-18 kg body weight)[2]
Dosage:0.3, 1, 3, and 10 mg/kg
Administration:I.v. infusions
Result:Demonstrated antiarrhythmic effects at 0.3 and 3.0 mg/kg.
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